Principles and Practice of Clinical Research
By helping researchers improve their clinical research skills in a highly interactive environment, PPCR promotes personal and professional growth and helps participants become more effective in their work.
Please note that the 2025 Main Course is now closed for applications.

Main Course
Principles and Practice of Clinical Research Main Course
Online, Distance-Learning Program (March 27—December 11, 2025)
Please note that the 2025 Main Course is closed for Applications
Optional Workshops for PPCR Participants
3-Day Advanced Statistical Workshop (On-Site | July 28-30, 2025)
- For PPCR Participants: $1,600
- For Non-PPCR Participants: $2,600
Research Manuscript Writing Workshop (On-Site | July 31 – August 1, 2025)
- For PPCR Participants: $1,100
- For Non-PPCR Participants: $1,600
5-Day Immersion Course (On-Site | Nov. 19-23, 2025 | Included in Main Course tuition)
Program Overview
By helping researchers improve their skills in clinical research in a highly interactive environment, Principles and Practice of Clinical Research (PPCR) will promote personal and professional growth and help participants become more effective in their work. We also expect that the interactive environment of the program will promote connections between participants and help foster future collaborative, multi-center projects.
This comprehensive educational experience is structured around the 9-month Main Course and a series of intensive, optional workshops.

The Program
Clinical research is vital for advancement in medicine, yet in most medical specialties – and in many countries – its tools are used inappropriately, resulting in invalid results.

Format
This program combines live and online interactions through web and on-site centers. Participants engage in weekly three-hour interactive videoconference sessions broadcast live on Zoom.

Learning Outcomes
Participants will develop skills in two main domains: design and conduct of clinical research, and interpretation and critical understanding of published research.
History of PPCR
Principles and Practice of Clinical Research was founded and directed by renowned neuroscientist, scholar, and professor Dr. Felipe Fregni in 2007 with some colleagues from University of Sao Paulo (Dr. Marta Imamura, Dr. Wu Hsing, and Dr. Linamara Battistella). PPCR has been intensively developed over these 17 years to offer an optimized learning environment for clinical researchers globally. PPCR alumni have become successful clinical researchers and continue the mission of teaching clinical research thus perpetuating the mission of PPCR. We welcome you to be a part of this journey with us! PPCR is currently offered by Harvard T.H. Chan School of Public Health Executive and Continuing Education.
50+
Countries represented in PPCR
17
Years fostering cutting-edge education
4.7k+
Participants have completed PPCR successfully
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“This course definitely changed my way of reading and interpreting published studies and also gave me a better condition to perform my own studies. It was a nice, enriching and unforgettable experience.“